11,515 research outputs found

    Alignment and orientation of an adsorbed dipole molecule

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    Half-cycle laser pulse is applied on an absorbed molecule to investigate its alignment and orientation behavior. Crossover from field-free to hindered rotation motion is observed by varying the angel of hindrance of potential well. At small hindered angle, both alignment and orientation show sinusoidal-like behavior because of the suppression of higher excited states. However, mean alignment decreases monotonically as the hindered angle is increased, while mean orientation displays a minimum point at certain hindered angle. The reason is attributed to the symmetry of wavefunction and can be explained well by analyzing the coefficients of eigenstates.Comment: 4 pages, 4 figures, to appear in Phys. Rev. B (2004

    An experiment on the quantitative description of climatic element field by orthogonal functions

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    Quantitative description of climatic element field by orthogonal function

    Customer Concerns about Uncertainty and Willingness to Pay in Leasing Solar Power Systems

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    Although solar power systems are considered as one of the most promising renewable energy sources, some uncertain factors as well as the high cost could be barriers which create customer resistance. Leasing instead of purchase, as one type of product service system, could be an option to reduce consumer concern on such issues. This study focuses on consumer concerns about uncertainty and willingness to pay for leasing solar power systems. Conjoint analysis method is used to find part worth utilities and estimate gaps of willingness to pay between attribute levels, including various leasing time lengths. The results show the part worth utilities an d relative importance of four major attributes, including leasing time. Among concerns about uncertainties, government subsidy, electricity price, reliability, and rise of new generation solar power systems were found to be significantly related to the additional willingness-to-pay for a shorter leasing time. Cluster analysis is used to identify two groups standing for high and low concerns about uncertainty. People with more concerns tend to pay more for a shorter lease time

    Epigenomic views of innate lymphoid cells

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    The discovery of innate lymphoid cells (ILCs) with selective production of cytokines typically attributed to subsets of T helper cells forces immunologists to reassess the mechanisms by which selective effector functions arise. The parallelism between ILCs and T cells extends beyond these two cell types and comprises other innate-like T lymphocytes. Beyond the recognition of specialized effector functionalities in diverse lymphocytes, features typical of T cells, such as plasticity and memory, are also relevant for innate lymphocytes. Herein, we review what we have learned in terms of the molecular mechanisms underlying these shared functions, focusing on insights provided by next generation sequencing technologies. We review data on the role of lineage-defining- and signal-dependent transcription factors (TFs). ILC regulomes emerge developmentally whereas the much of the open chromatin regions of T cells are generated acutely, in an activation-dependent manner. And yet, these regions of open chromatin in T cells and ILCs have remarkable overlaps, suggesting that though accessibility is acquired by distinct modes, the end result is that convergent signaling pathways may be involved. Although much is left to be learned, substantial progress has been made in understanding how TFs and epigenomic status contribute to ILC biology in terms of differentiation, specification, and plasticity

    Navigating the web: a study on professional translators’ behaviour

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    Despite the importance of online information seeking behaviours being recognised by researchers (Enriquez Raido 2011, 2014, Gough 2015, Hvelplund 2017, 2019), there are only a handful of studies focusing on them. This study therefore sets out to investigate how professional translators conduct their primary action (i.e. query behaviour) and secondary action (i.e. browsing and clicking behaviour) in navigating the web. Unlike previous studies, it adopts a qualitative eye tracking methodology, i.e. eye tracking stimulated think-aloud with ten professional translators. A model of translators’ primary and secondary actions is presented as well as how these actions interact with one another as a result

    DLC2 modulates angiogenic responses in vascular endothelial cells by regulating cell attachment and migration.

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    Deleted in liver cancer 1 (DLC1) is a RhoGTPase activation protein-containing tumor suppressor that associates with various types of cancer. Although DLC2 shares a similar domain structure with that of DLC1, the function of DLC2 is not well characterized. Here, we describe the expression and ablation of DLC2 in mice using a reporter-knockout approach. DLC2 is expressed in several tissues and in endothelial cells (ECs) of blood vessels. Although ECs and blood vessels show no histological abnormalities and mice appear overall healthy, DLC2-mutant mice display enhanced angiogenic responses induced by matrigel and by tumor cells. Silencing of DLC2 in human ECs has reduced cell attachment, increased migration, and tube formation. These changes are rescued by silencing of RhoA, suggesting that the process is RhoA pathway dependent. These results indicate that DLC2 is not required for mouse development and normal vessel formation, but may protect mouse from unwanted angiogenesis induced by, for example, tumor cells

    Complete gradient-LC-ESI system on a chip for protein analysis

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    This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray ionization (LC-ESI) system on a chip. This chip integrates a pair of high-pressure gradient pumps, a sample injection pump, a passive mixer, a packed separation column, and an ESI nozzle. We also present the successful on-chip separation of protein digests by reverse phase (RP)-LC coupled with on-line mass spectrometer (MS) analysis
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